diff --git a/src/cmdforge/cli/__init__.py b/src/cmdforge/cli/__init__.py
index 9779f00..3ebb9fe 100644
--- a/src/cmdforge/cli/__init__.py
+++ b/src/cmdforge/cli/__init__.py
@@ -12,7 +12,7 @@ from .tool_commands import (
 from .provider_commands import cmd_providers
 from .registry_commands import cmd_registry
 from .collections_commands import cmd_collections
-from .project_commands import cmd_deps, cmd_deps_tree, cmd_install_deps, cmd_add, cmd_init, cmd_lock, cmd_verify
+from .project_commands import cmd_deps, cmd_deps_tree, cmd_install_deps, cmd_add, cmd_remove, cmd_init, cmd_lock, cmd_verify
 from .config_commands import cmd_config
 
 
@@ -323,6 +323,11 @@ def main():
     p_add.add_argument("--no-install", action="store_true", help="Don't install after adding")
     p_add.set_defaults(func=cmd_add)
 
+    # 'remove' command
+    p_remove = subparsers.add_parser("remove", help="Remove a tool from project dependencies")
+    p_remove.add_argument("tool", help="Tool to remove (owner/name or just name)")
+    p_remove.set_defaults(func=cmd_remove)
+
     # 'init' command
     p_init = subparsers.add_parser("init", help="Initialize cmdforge.yaml")
     p_init.add_argument("-n", "--name", help="Project name")
diff --git a/src/cmdforge/cli/project_commands.py b/src/cmdforge/cli/project_commands.py
index e197dcf..eb876ee 100644
--- a/src/cmdforge/cli/project_commands.py
+++ b/src/cmdforge/cli/project_commands.py
@@ -416,6 +416,39 @@ def cmd_add(args):
     return 0
 
 
+def cmd_remove(args):
+    """Remove a tool from project dependencies."""
+    tool_spec = args.tool
+
+    # Find manifest
+    manifest_path = find_manifest()
+    if not manifest_path:
+        print("No cmdforge.yaml found in current project.")
+        print("Nothing to remove.")
+        return 1
+
+    manifest = load_manifest(manifest_path)
+
+    # Parse tool spec to get the name
+    parsed = ToolSpec.parse(tool_spec)
+    tool_name = parsed.full_name
+
+    # Remove from manifest
+    if manifest.remove_dependency(tool_name):
+        save_manifest(manifest, manifest_path)
+        print(f"Removed {tool_name} from {manifest_path.name}")
+    else:
+        # Try without owner prefix
+        if manifest.remove_dependency(parsed.name):
+            save_manifest(manifest, manifest_path)
+            print(f"Removed {parsed.name} from {manifest_path.name}")
+        else:
+            print(f"Dependency '{tool_name}' not found in {manifest_path.name}")
+            return 1
+
+    return 0
+
+
 def cmd_init(args):
     """Initialize a new cmdforge.yaml."""
     manifest_path = Path.cwd() / MANIFEST_FILENAME
diff --git a/src/cmdforge/manifest.py b/src/cmdforge/manifest.py
index 3447189..133e80e 100644
--- a/src/cmdforge/manifest.py
+++ b/src/cmdforge/manifest.py
@@ -141,6 +141,31 @@ class Manifest:
 
         self.dependencies.append(Dependency(name=name, version=version))
 
+    def remove_dependency(self, name: str) -> bool:
+        """Remove a dependency by name.
+
+        Args:
+            name: Tool name (can be qualified like 'official/tool' or just 'tool')
+
+        Returns:
+            True if dependency was removed, False if not found
+        """
+        # Try exact match first
+        for i, dep in enumerate(self.dependencies):
+            if dep.name == name:
+                self.dependencies.pop(i)
+                return True
+
+        # Try matching just the tool name part (without owner)
+        short_name = name.split("/")[-1] if "/" in name else name
+        for i, dep in enumerate(self.dependencies):
+            dep_short = dep.name.split("/")[-1] if "/" in dep.name else dep.name
+            if dep_short == short_name:
+                self.dependencies.pop(i)
+                return True
+
+        return False
+
 
 def find_manifest(start_dir: Optional[Path] = None) -> Optional[Path]:
     """